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Statistical Analysis

TCAG Facilities

Biobanking
Cytogenomics and Genome Resources
DNA Sequencing/Synthesis
Genetic Analysis
Informatics
Microarray Analysis
Statistical Analysis

Conference Abstracts and Presentations

  1. X Song, P Hu, R Torra, DC Cattran, AD Paterson, YP Pei (2012) Homozygosity mapping for steroid-sensitive nephrotic syndrome. The Annual Meeting of American Society of Nephrology, San Diego, California, USA, November 2012.
  2. P Hu, AD Paterson. Dynamic pathway analysis of genes associated with blood pressure using whole genome sequence data. Genetic Analysis Workshop (GAW18), Stevenson, WA, USA, October 2012.
  3. MR Nicole, D Andriy, JS Lisa (2012) Association analysis with sequence data using publicly available controls. Genetic Analysis Workshop (GAW18), Stevenson, WA, USA, October 2012.
  4. P Hu, MMG Seno, SW Scherer (2012) A pathway-based meta-analysis approach for integrating autism gene expression profiles. NeuroDevNet's 3rd Annual Brain Development Conference, Toronto, Ontario, Canada, September 2012.
  5. U Allen, P Hu, S Pereira, J Beyene, D Ho, N Khodai-Booran, T Nalpathamkalam, S Read (2012) Exploring genetic diversity of Epstein-Barr Virus (EBV) using whole genome next generation sequencing. International Congress on Oncogenic Herpesviruses and Associated Diseases, Philadelphia, Pennsylvania, USA, August 1-4, 2012.
  6. D Picard, S Millar, C Hawkins, H Rogers, SK Kim, YS Ra, T Chan, J Fangusaro, H Toledano, H Nakamura,T Van Meter, J Hayden, J Chan, L Lafay-Cousin, P Hu, S Goldman, CC Lau, S Pomeroy, HK Ng, J Pang, C Jones, A Gajjar, S Clifford, S Pfister, C Eberhart, E Bouffet, R Grundy, A Huang (2012) Markers of cell lineage correlate with survival and metastatic potential in CNS-PNET. 15th International Symposium on Pediatric Neuro-Oncology, Toronto, ON, Canada, June 24-27, 2012.
  7. CC dos Santos, S Murthy, P Hu, Y Shan, JJ Haitsma1, SHJ Mei, DJ Stewart, WC Liles (2012) Network analysis of transcriptional response induced by systemic administration of bone marrow derived mesenchymal cells in polymicrobial sepsis. American Thoracic Society Annual Meeting, San Francisco, CA, USA. May 18-23, 2012.
  8. E Papp, R Johnson, D Merico, P Hu, I Grandal, C Guidos, J Danska (2012) A novel ligand-independent Flt3 allele drives RANKL expression in a murine model of B-precursor acute lymphoblastic leukemia with CNS dissemination. American Association for Cancer Research Annual Meeting, Chicago, IL, USA. March 31- April 4, 2012.
  9. N Kanwar, P Hu, M Clemons, D McCready, SJ Done (2012) Identification of frequently gained genomic regions in breast circulating tumor cells. American Association for Cancer Research Annual Meeting, Chicago, IL, USA. March 31- April 4, 2012.
  10. P Hu (invited guest speaker). A comparative analysis of statistical approaches for biomarker discovery using microbiome data. Methods to Study the Human Microbiome: Workshop II, Toronto, Canada, October 2011.
  11. R Johnson, P Hu, C Fan, C Anders (2011) Gene expression as a predictor of "young adult type" breast cancer: a retrospective analysis. LIVESTRONG Young Adult Alliance Annual Meeting, Austin, TX, USA. November 2011.
  12. Z Wei, W Wang, P Hu, GJ Lyon, H Hakonarson (2011) SNVer: a statistical tool for variant calling in analysis of pooling or individual next-generation sequencing data. The American Society of Human Genetics (ASHG) Annual Meeting, Montreal, Canada, October 2011 (Platform Oral Presentation).
  13. P Hu, C Sandhu, Z Wei, E Cheran, J Foong, L Lau, Z Wang, S Pereira, Z Hu, RF Wintle, AD Paterson, SW Scherer (2011) Next generation Resequencing of pooled DNA samples identified variants of SHANK3 in autism spectrum disorder. Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting. King City, Canada, May 2011.
  14. Ye Yang, P Hu, Z Wang, SW Scherer (2011) Combining sparse principal component analysis and LASSO to identify autism spectrum disorder associated risk pathways via rare copy number variants. Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting. King City, Canada, May 2011.
  15. JE Below, J Morrison, E Gamazon, A Konkash-Baev, A Valladares, J Barta, K Ross, M Edwards, N Wacher, J Garcia-Mena, P Hu, TD Dyer, J Kumate, M Cruz, R Duggirala, MA Carless, A Pluzhnikov J Escobedo, PM Mckeigue, JE Curran,DM Hallman, MD Shriver, G Bell, J Blangero, E Parra, C Hanis, N Cox (2010) First Meta-Analysis of Type 2 diabetes in Mexicans and Mexican-Americans. Diabetes, 59 (Suppl. 1A), 57-LB. Presented at 70th Scientific Sessions of American Diabetes Association, Orlando, USA, June 2010.
  16. X Song, P Hu, N He, AD Paterson, Y Pei (2010) Homozygosity mapping of recessive disease genes for steroid-sensitive nephrotic syndrome. The Annual Meeting of American Society of Nephrology, Denver, USA, November 2010.
  17. MA Tayeb, RM Iwasiow, P Hu, RF Wintle, SW Scherer (2010) Evaluation of the performance of genomic DNA from saliva collected with Oragene-DNA for the purpose of SNP discovery on various Illumina Technologies. The American Society of Human Genetics (ASHG) Annual Meeting, Washington, USA, November 2010.
  18. RM Iwasiow, MA Tayeb, P Hu, RF Wintle, SW Scherer (2010) Evaluation of the performance of gDNA from saliva collected with Oragene-DNA for the purpose of CNV analysis on the Agilent Human Genome CGH Array 244A. The American Society of Human Genetics (ASHG) Annual Meeting, Washington, USA, November 2010.
  19. U Allen, M Barton-Forbes, J Beyene, P Hu, N Khodai-Booran, D Héber, A Diphchand, V Ng, M Soloman, D Grant (2009) Host gene expression in Epstein-Barr Virus (EBV) infection after pediatric organ transplantation. Pediatric Transplantation 13, S1 7 - 43. Presented at 5th Congress of the International Pediatric Transplant Association, Istanbul, Turkey, April 2009.
  20. B Kabakchiev, D Turner, JS Hyams, DR Mack, NS LeLeiko, W Crandall, J Markowitz, AR Otley, W Xu, P Hu, AM Griffiths, MS Silverberg (2009) Gene expression profiles associated with lack of response to intravenous corticosteroids in children with severe ulcerative colitis. Gastroenterology 136 (Suppl.), A-172. Presented at Digestive Disease Week (DDW), Chicago, USA, May 2009.
  21. J Li, W Xuan, P Hu, RK Kharbanda, AN Redington (2009) Remote ischemic preconditioning modifies cardiac microRNA expression in Vivo: first observations in a mouse model. Journal of the American College of Cardiology 53 (Suppl.), A310. Presented at The American College of Cardiology 58th Annual Scientific Conference, Orlando, USA, and March 2009.
  22. RM Iwasiow, C James, P Hu, RF Wintle, SW Scherer (2009) Evaluation of performance of gDNA from saliva collected with Oragene-DNA for the purpose of SNP and CNV analysis on the Affymetrix Genome-wide Human SNP Array 6.0. The American Society of Human Genetics (ASHG) Annual Meeting, Hawaii, USA, October 2009.
  23. B Kabakchiev, D Turner, J Hyams, D Mack, N Leleiko, W Crandall, J Markowitz, A Otley, W Xu, P Hu, A Griffiths, MS Silverberg (2010) Gene expression profiles associated with lack of response to intravenous corticosteroid in children with severe ulcerative colitis. The American Society of Human Genetics (ASHG) Annual Meeting, Hawaii, USA, October 2009.
  24. MMG Seno, CR Marshall, P Hu, J McDonald, T Paton, G Gasallo, SW Scherer (2009) The effect of large de novo chromosomal deletions on gene expression. The American Society of Human Genetics (ASHG) Annual Meeting, Hawaii, USA, October 2009.
  25. D Pinto, J Zhang, B Thiruvahindrapduram, Z Wang, L Feuk, P Hu, CMT Greenwood, SW Scherer (2008) A robust copy number variation discovery algorithm for multiple array platforms. The American Society of Human Genetics (ASHG) Annual Meeting, Philadelphia, USA, November 2008.
  26. X Wang, P Hu, M Cameron, M Anraku, M Cypel, Y Imai, J Penninger, AAS Slutsky, D Kelvin, S Keshavjee, J Beyene, CMT Greenwood, C dos Santos (2008) Cross-species, cross-platform meta-analysis of acute lung injury microarrays and validation of injury expression profiles in human models of lung transplantation. 16th Annual International Conference Intelligent Systems for Molecular Biology (ISMB'08). Toronto, Canada, July 2008.
  27. P Hu, I Matei, E Parkhomenko, C Guidos, J Danska, J Beyene (2008) Evaluation of CNV calling algorithms in identifying T-ALL related cancer genes. Genetic Epidemiology 32, 696. Presented at International Genetic Epidemiology Society 17th Annual Meeting, St. Louis, Missouri, USA, September 2008.
  28. E Parkhomenko, D Tritchler, P Hu, C Guidos, J Danska, J Beyene (2008) Studying genomic impact of copy number variation on gene expression profiles using sparse canonical correlation analysis. Genetic Epidemiology 32, 710. Presented at International Genetic Epidemiology Society 17th Annual Meeting, St. Louis, Missouri, USA, September 2008.
  29. I Sung, T Kim, T Kim, B Lee, L Peddle, P Rahman, C Greenwood, P Hu, R Inman (2008) IL-23R Polymorphisms in patients with ankylosing spondylitis in Korea. Annals of the Rheumatic Diseases 67 (Suppl. II), 509. Presented at Annual European Congress of Rheumatology, Paris, June 2008.
  30. MMG Seno, D Pinto, CR Marshall, T Paton, J Skaug, P Hu, G Casallo, K Lee, B Thiruvahindrapduram, SW Scherer (2008) Dysregulation of microRNAs and genes in autism spectrum disorder. 2008 Neuroscience Meeting, Washington, DC., USA, November 2008.
  31. P Hu, J Beyene, CMT Greenwood (2007) Discovering regulatory modules from eQTL data. Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting. Toronto, Canada, April 2007.
  32. Muhammad A Rafiq, C Marshall, P Hu, M Ansar, A Mowjoodi, L Fuke, SW Scherer (2007) A novel locus for autosomal recessive mental retardation maps to 2p25.3-25.2 in a consanguineous Pakistani family. HUGO's 12th Human Genome Meeting (HGM), Montreal, Canada, May 2007.
  33. N Khodai-Booran, J Beyene, M Barton-Forbes, P Hu, D Hébert, A Dipchand, V Ng, D Grant, A Fecteau, M Soloman, B Ngan, S Read, S Weitzman, U Allen (2006) Preliminary assessment of gene expression profiling using DNA microarray technology in patients at risk of epstein-barr virus (EBV) Lymphoproliferation after Transplantation. American Journal of Transplantation 6(Suppl. 2), 869. Presented at World Transplant Congress. Boston, MA, USA, July 2006.
  34. P Hu, CMT Greenwood, J Beyene (2006) Pathway-based models for predicting prostate cancer by integrative analysis of gene expression data. BioC2006-Where Software and Biology Connect. Fred Hutchinson Cancer Research Center, Seattle, WA, USA, August 2006.
  35. P Hu, J Beyene, CMT Greenwood (2006) Genetic analysis of gene expression variation in human cell lines. Statistical Genetics: From Haplotype Maps to Disease Susceptibility Genes, The University of Hong Kong, February 2006.
  36. P Hu, CMT Greenwood, J Beyene (2005) Identifying prognostic gene expression signatures by meta-analysis of microarray data sets for improved prediction of prostate cancer. Donnelly CCBR/MaRS Joint Opening Scientific Symposium on Computational & Chemical Biology, Toronto, September 2005.
  37. J Beyene, P Hu, CMT Greenwood (2005) Data Integration Method for High-throughput Data. Joint Statistical Meetings (JSM), Minneapolis, USA, August 2005.