Genescript Annotation Pipeline

About

Genescript is an annotation pipeline developed at The Centre for Applied Genomics at The Hospital for Sick Children in Toronto Canada. It's main features are gene prediction, EST homology searching, and comparative homology searching. Advanced functionality includes clustering of ESTs from dbEST, accurate EST to genomic alignments using Sim4, and a scoring system which identifies highly probable predictions.

It is free for academic users and only uses programs which are also free for academic use.

Reference

Bioinformatics. 2003 Jun 12;19(9):1177-8.

Genescript: DNA sequence annotation pipeline.

Hudek AK, Cheung J, Boright AP, Scherer SW.

Department of Genetics, The Hospital for Sick Children, Room 9107, Toronto, Ontario, M5G 1X8, Canada. School of Computer Science, University of Waterloo, Ontario, N2L 3G1, Canada.

Summary: Genescript uses a number of publicly available analysis programs to annotate a DNA sequence. It provides an integrated display of results from each program, and includes an evidence-based scoring system that gives informative summaries of predicted gene models.

PMID: 12801881

Contact Information

Please direct any questions to

Alexander K. Hudek
The Hospital for Sick Children
Room 9107, Department of Genetics
555 University Avenue
Toronto, Ontario, M5G 1X8, Canada
Fax (416) 813-8319
E-mail: alex@genet.sickkids.on.ca