Websites:
The Centre for Applied Genomics
The Chromosome 7 Project
Database of Genomic Variants
McLaughlin Centre
Steve Scherer's Wiki

News:
Press Releases and Articles
Lay Reviews/Opinions/Editorials
Media/Scientific News Articles
Interviews
Video presentation and interview
Integrative research at TCAG [Video]

Contact Info:
Stephen W. Scherer
The Centre for Applied Genomics
The Hospital for Sick Children
Peter Gilgan Centre for Research and Learning
686 Bay Street, Room 13.9800
Toronto, Ontario, M5G 0A4, Canada
(416) 813-7613 (office)
(416) 813-8319 (fax)

Elaine Chang
Dr. Scherer's Assistant
Phone: (416) 813-7654 x301574
Fax: (416) 813-8319

1. Lohi H, Chan EM, Scherer SW, Minassian BA. On the road to tractability: the current biochemical understanding of progressive myoclonus epilepsies. Adv Neurol. 2006;97:399-415. [PMID: 16383151]
2. Feuk L, Carson AR, Scherer SW. Structural variation in the human genome. Nat Rev Genet. 2006 Feb;7(2):85-97. [PMID: 16418744]
3. Zeesman S, Nowaczyk MJ, Teshima I, Roberts W, Cardy JO, Brian J, Senman L, Feuk L, Osborne LR, Scherer SW. Speech and language impairment and oromotor dyspraxia due to deletion of 7q31 that involves FOXP2. Am J Med Genet A. 2006 Mar 1;140(5):509-14. [PMID: 16470794]
4. Carson AR, Cheung J, Scherer SW. Duplication and relocation of the functional DPY19L2 gene within low copy repeats. BMC Genomics. 2006 Mar 9;7:45. [PMID: 16526957]
5. Vincent JB, Horike SI, Choufani S, Paterson AD, Roberts W, Szatmari P, Weksberg R, Fernandez B, Scherer SW. An inversion inv(4)(p12-p15.3) in autistic siblings implicates the 4p GABA receptor gene cluster. J Med Genet. 2006 May;43(5):429-34. Epub 2006 Mar 23. [PMID: 16556609]
6. Feuk L, Marshall CR, Wintle RF, Scherer SW. Structural variants: changing the landscape of chromosomes and design of disease studies. Hum Mol Genet. 2006 Apr 15;15 Spec No 1:R57-66. Review. [PMID: 16651370]
7. Perry GH, Tchinda J, McGrath SD, Zhang J, Picker SR, Caceres AM, Iafrate AJ, Tyler-Smith C, Scherer SW, Eichler EE, Stone AC, Lee C. Hotspots for copy number variation in chimpanzees and humans. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8006-11. Epub 2006 May 15. [PMID: 16702545]
8. Freeman JL, Perry GH, Feuk L, Redon R, McCarroll SA, Altshuler DM, Aburatani H, Jones KW, Tyler-Smith C, Hurles ME, Carter NP, Scherer SW, Lee C. Copy number variation: new insights in genome diversity. Genome Res. 2006 Aug;16(8):949-61. Epub 2006 Jun 29. Review. [PMID: 16809666]
9. Schwarzbraun T, Windpassinger C, Ofner L, Vincent JB, Cheung J, Scherer SW, Wagner K, Kroisel PM, Petek E. Genomic analysis of five chromosome 7p deletion patients with Greig cephalopolysyndactyly syndrome (GCPS). Eur J Med Genet. 2006 Jul-Aug;49(4):338-45. Epub 2005 Nov 28. [PMID: 16829355]
10. Khaja R, MacDonald JR, Zhang J, Scherer SW. Methods for identifying and mapping recent segmental and gene duplications in eukaryotic genomes. Methods Mol Biol. 2006;338:9-20. [PMID: 16888347]
11. Okamura K, Feuk L, Marques-Bonet T, Navarro A, Scherer SW. Frequent appearance of novel protein-coding sequences by frameshift translation. Genomics. 2006 Aug 3; [Epub ahead of print] PMID: 16890400 [PubMed - as supplied by publisher]
12. Wilson MD, Cheung J, Martindale DW, Scherer SW, Koop BF. Comparative analysis of the paired immunoglobulin-like receptor (PILR) locus in six mammalian genomes: duplication, conversion, and the birth of new genes. Physiol Genomics. 2006 Aug 22; [PMID: 16926269]
13. Osborne LR, Joseph-George AM, Scherer SW. Williams-Beuren syndrome diagnosis using fluorescence in situ hybridization. Methods Mol Med. 2006;126:113-28. [PMID: 16930009]
14. Andrade DM, Scherer SW, Minassian BA. Protein therapy for Unverricht-Lundborg disease using cystatin B transduction by TAT-PTD Is it that simple? Epilepsy Res. 2006 Aug 21; [PMID: 16930946]
15. Kwasnicka-Crawford DA, Roberts W, Scherer SW. Characterization of an Autism-Associated Segmental Maternal Heterodisomy of the Chromosome 15q11-13 Region. J Autism Dev Disord. 2006 Sep 28; [PMID: 17006779]
16. Petek E, Schwarzbraun T, Noor A, Patel M, Nakabayashi K, Choufani S, Windpassinger C, Stamenkovic M, Robertson MM, Aschauer HN, Gurling HM, Kroisel PM, Wagner K, Scherer SW, Vincent JB. Molecular and genomic studies of IMMP2L and mutation screening in autism and Tourette syndrome. Mol Genet Genomics. 2006 Oct 17; [PMID: 17043892]
17. Kwasnicka-Crawford DA, Carson AR, Scherer SW. IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein. Biochem Biophys Res Commun. 2006 Oct 4; [PMID: 17045569]
18. Zhang J, Feuk L, Duggan GE, Khaja R and Scherer SW 2006. Development of bioinformatics resources for display and analysis of copy number and other structural variants in the human genome. Cytogenetic and Genome Research, 115, 205-214. [PMID: 17124402]
19. Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman J, Gonzalez JR, Gratacos M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, *Scherer SW and *Hurles ME. Global variation in copy number in the human genome. Nature. Nov 23 [PMID: 17122850] *corresponding authors.
20. Fiegler H, Redon R, Andrews D, Scott C, Andrews R, Carder C, Clark R, Dovey O, Ellis P, Feuk L, French L, Hunt P, Kalaitzopoulos D, Larkin J, Montgomery L, Perry GH, Plumb BW, Porter K, Rigby RE, Rigler D, Valsesia A, Langford C, Humphray SJ, Scherer SW, Lee C, Hurles ME, Carter, NP 2006 Accurate and reliable high-throughput detection of copy number variation in the human genome Genome Research Nov 22 [PMID: 17122085]
21. Komura D, Shen F, Ishikawa S, Fitch KR, Chen W, Zhang J, Liu G, Ihara S, Nakamura H, Hurles ME, Lee C, Scherer SW, Jones KW, Shapero MH, Huang J and Aburatani H 2006 Genome-wide detection of human copy number variations using high density DNA oligonuceotide arrays Genome Research Nov 22 [PMID: 17122084]
22. Khaja R, Zhang J, MacDonald JR, He Y, Joseph-George AM, Wei J, Rafiq MA, Qian C, Shago M, Pantano L, Aburatani H, Jones K, Redon R, Hurles M, Armengol L, Estivill X, Mural RJ, Lee C, *Scherer SW and Feuk L Genome assembly comparison to identify structural variants in the human genome Nature Genetic Nov 22 [PMID: 17115057] *corresponding author