Web sites:
The Centre for Applied Genomics
The Chromosome 7 Project
Database of Genomic Variants
News:
Press Releases and Articles
Lay Reviews/Opinions/Editorials
Media/Scientific News Articles
Interviews
Video presentation and interview
Integrative research at
TCAG [Video]
Contact Info:
Stephen W. Scherer
The Centre for Applied Genomics
The Hospital for Sick Children
14th Floor, Toronto Medical Discovery Tower/MaRS Discovery District
101 College St., Toronto, Ontario, M5G 1L7, Canada
(416) 813-7613 (office)
(416) 813-8319 (fax)
Jenny Kaderali,
Dr. Scherer's Assistant
Phone: (416) 813-7654 x1574 Fax: (416) 813-8319
Publications (1988 - 1995)
- Dowhanick, T.M., Scherer, S.W., Willick, G., Russell, I., Stewart, G.G. and Seligy, V.L. 1988. Differetial glucoamylase expression in Schwanniomyces castellii induced by maltose. Canadian Journal of Microbiology 34, 262-270.
- Dowhanick, T.M., Russell, I., Scherer, S.W., Stewart, G.G. and Seligy, V.L. 1990. Expression and regulation of glucoamylase from the yeast Schwanniomyces castellii. Journal of Bacteriology 172, 2360-2366. [PMID: 2110140]
- Scherer, S.W., Otulakowski, G., Robinson, B.H. and Tsui, L-C. 1991. Localization of the human dihydrolipoamide dehydrogenase gene (DLD) to 7q31-32. Cytogenetics and Cell Genetics 56, 176-177. [PMID: 2055113]
- Scherer, S.W., Tompkins, B.J.F. and Tsui, L.-C. 1992. A human chromosome 7-specific genomic DNA library in yeast artificial chromosomes. Mammalian Genome 3, 179-181. [PMID: 1617225]
- Scherer, S.W., Rommens, J.M., Soder, S., Wong, E., Plasvic, N., Tompkins, B.J.F., Beattie, A., Kim, J. and Tsui, L.-C. 1993. Refined localization and yeast artificial chromosome (YAC) contig-mapping of genes and DNA segments in the 7q21-q32 region. Human Molecular Genetics 2, 751-760. [PMID: 8353494]
- Scherer, S.W., Neufeld, E.J., Lievens, P.M-J., Orkin, S.H., Kim, J. and Tsui, L.-C. 1993. Regional localization of the CCAAT displacement protein gene (CUTL1) to 7q22 by analysis of somatic cell hybrids. Genomics 15, 695-696. [PMID: 8468066]
- Guirrieri, F., Trask, B., van den Engh, G., Krauss, C.M., Schinzel, A., Pettenati, M.J., Shindler, D., Dietz-Band, J., Vergnaud, G., Scherer, S.W., Tsui, L.-C. and Muenke, M. 1993. Physical mapping of the holoprosencephaly critical region in 7q36. Nature Genetics 3, 247-251. [PMID: 8485580]
- Marsden, P.A., Heng, H.H.Q., Scherer, S.W., Stewart, R.J., Hall, A.V., Shi, X.M., Tsui, L.-C. and Schappert, K. 1993. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. Journal of Biological Chemistry 268, 17478-17488. [PMID: 7688726]
- Peichel, C.L., Scherer, S.W., Tsui, L.-C., Beier, D.R. and Vogt, T. F. 1993. Mapping the midkine family of developmentally regulated signalling molecules. Mammalian Genome 4, 632-638. [PMID: 8281012]
- Heng, H.H.Q., Shi, X-M., Scherer, S.W., Andrulis, I. and Tsui, L.C. 1994. Refined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/K015. Cytogenetics and Cell Genetics 66, 135-138. [PMID: 7904551]
- Powers, P., Scherer, S.W., Tsui, L.-C., Gregg, R. and Hogan, K. 1994. Localization of the gene encoding the alpha 2/delta subunit (CACNL2A) of the human skeletal muscle voltage-dependent Ca2+ channel to chromosome 7q21-q22 by somatic cell hybrid analysis. Genomics 19, 192-193. [PMID: 8188232]
- Vamvakopoulos, N.C., Kunz, J., Olberding, U., Scherer, S.W., Sioutopoulou, O., Schneider, V., Durkin, S. and Nierman, W.C. 1994. Mapping the human growth hormone-releasing hormone receptor (GHRHR) gene to the short arm of chromosome 7 (7p13-21) near the epidermal growth factor receptor (EGFR) gene. Genomics 20, 338-340. [PMID: 8020995]
- Scherer, S.W., Poorkaj, P., Allen, T., Kim, J., Geshuri, D., Nunes, M., Soder, S., Pagon, R., Stephens, K., Patton, M., Rivera, H., Berg, M.A., Pfeiffer, R.A., Naritomi, K., Hughes, H., Genuardi, M., Gurrieri, F., Neri, G., Lovrein, E., Magenis, E., Tsui, L.-C. and Evans, J.P. 1994. Fine mapping of the autosomal dominant split hand/split foot locus on chromosome 7 band q21.3-q22.1. American Journal of Human Genetics 55, 12-20. [PMID: 8023840]
- Palmer, S., Scherer, S.W., Kukolich, M., Wijsman, E.M., Tsui, L.-C., Stephens, K. and Evans, J.P. 1994.
Evidence for locus heterogeneity in human autosomal dominant split hand/split foot malformation. American Journal of Human Genetics 55, 21-26. [PMID: 7912888]
- Kunz, J.*, Scherer, S.W.*, Klawitz, I., Soder, S., Du, Y-Z., Speich, N., Kalff-Suske, M., Heng, H., Tsui, L.-C. and Grzeschik, K.-H. 1994. Regional localization of 725 human chromosome 7-specific yeast artificial chromosome clones. Genomics 22, 439-448. *contributed equally to the manuscript. [PMID: 7806232]
- Scherer, S.W., Poorkaj, P., Trask, B., Soder, S., Allen, T., Nunes, M., Geshuri, D., Wong, E., Belloni, E., Little, S., Zhou, L., Becker, D., Kere, J., Ignatius, J., Niikawa, N., Fukushima, Y., Hasegawa, T., Weissenbach, J., Boncinelli, E., Massa, H., Tsui, L.-C. and Evans, J.P. 1994. Physical mapping of the split hand/split foot locus on chromosome 7 and implication in syndromic ectrodactyly. Human Molecular Genetics 3, 1345-1354. [PMID: 7987313]
- Iles, D.E., Lehmann-Horn, F., Scherer, S.W., Tsui, L.-C., Olde Weghuis, D., Suijkerbuijk, R.F., Heytens, L., Mikala, G., Schwartz, A., Ellis, F.R., Stewart, A.D. and Wieringa, B. 1994. Localization of the gene encoding the alpha 2/delta-subunits of the L-type voltage-dependent calcium channel to chromosome 7q and analysis of the segregation of flanking markers in malignant hyperthermia susceptible families. Human Molecular Genetics 3, 969-975. [PMID: 7951247]
- Thacker J., Tambini, C. E., Simpson, P.J., Tsui, L.-C. and Scherer, S.W. 1995. Localization to chromosome 7q36.1 of the human XRCC2 gene, determining sensitivity to DNA-damaging agents. Human Molecular Genetics 4, 113-120. [PMID: 7711722]
- Scherer, S.W., Heng, H.H.Q., Robinson, G.W., Mahon, K. A., Evans, J.P. and L.-C. Tsui. 1995. Assignment of the human homolog of mouse Dlx-3 to chromosome 17q21.3-q22 by analysis of somatic cell hybrids and fluorescence in situ hybridization. Mammalian Genome 6, 310-311. [PMID: 7613049]
- Barron-Casella, E.A., Torres, M.A., Scherer, S.W., Heng, H.H.Q., Tsui, L.-C. and Casella, J.F. 1995. Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin families. Journal of Biological Chemistry 270, 21472-21479. [PMID: 7665558]
- Alley, T.L., Gray, B.A., Lee, S., Scherer, S.W., Tsui, L.-C., Tint, G.S., Williams, C.A., Zori, R. and Wallace, M.R. 1995. Identification of a yeast artificial chromosome clone spanning the translocation breakpoint at 7q32.1 in a Smith-Lemli-Opitz Syndrome Patient. American Journal of Human Genetics 56, 1411-1416. [PMID: 7762564]
- Torigue, K., Sato, S., Kusaba, H., Kohno, K., Kuwano, M., Okumura, K., Green, E., Tsui, L.-C., Scherer, S.W., Schlessinger, D. and Wada, M. 1995. A YAC-based contig of 1.5 Mb spanning the human multidrug resistance gene region and delineating the amplification unit in three human multidrug-resistant cell lines. Genome Research 5, 233-244. [PMID: 8593611]