Websites:
The Centre for Applied Genomics
The Chromosome 7 Project
Database of Genomic Variants
McLaughlin Centre
Steve Scherer's Wiki

News:
Press Releases and Articles
Lay Reviews/Opinions/Editorials
Media/Scientific News Articles
Interviews
Video presentation and interview
Integrative research at TCAG [Video]

Contact Info:
Stephen W. Scherer
The Centre for Applied Genomics
The Hospital for Sick Children
Peter Gilgan Centre for Research and Learning
686 Bay Street, Room 13.9800
Toronto, Ontario, M5G 0A4, Canada
(416) 813-7613 (office)
(416) 813-8319 (fax)

Elaine Chang
Dr. Scherer's Assistant
Phone: (416) 813-7654 x301574
Fax: (416) 813-8319

1. Jerome, C.A., Scherer, S.W., Tsui, L.-C., Gietz, R.D. and Triggs-Raine, B. 1997. Assignment of growth factor receptor-bound protein 10 (GRB10) to human chromosome 7p11.2-p12. Genomics 40, 215-216. [PMID: 9070953]
2. Fischer, K., Fröhling, S., Scherer, S.W., McAllister Brown, J., Scholl, C., Stilgenbauer, S., Tsui, L.-C., Lichter, P. and Döhner, H. 1997. Molecular cytogenetic delineation of deletions and translocations involving chromosome band 7q22 in myeloid leukemias. Blood 89, 2036-2041. [PMID: 9058725]
3. Alley, T.L., Scherer, S.W., Huizenga, J.J., Tsui, L.-C. and Wallace, M.R. 1997. Physical mapping of the chromosome 7 breakpoint region in an SLOS patient with t(7;20)(q32.1;q13.2). American Journal of Medical Genetics 68, 279-281. [PMID: 9024559]
4. Zeng, W.R., Scherer, S.W., Koutsilieris, M., Huizenga, J.J., Filteau, F., Tsui, L.-C. and Nepveu, A. 1997. Loss of heterozygosity and reduced expression of the CUTL1 gene in uterine leiomyomas. Oncogene 14, 2355-2365. [PMID: 9178912]
5. Schmidt, L., Duh, F.-M., Chen, F., Kishida, T., Glenn, G., Choyke, P., Scherer, S.W., Zhuang, Z., Lubensky, I., Dean, M., Allikmets, R., Chidambaram, A., Bergerheim, U.R., Feltis, J.T., Casadevall, C., Zamarron, A., Bernues, M., Richard, S., Lips, C.J.M., Walther, M.M., Tsui, L.-C., Geil, L., Orcutt, M.L., Stackhouse, T., Lipan, J., Slife, L., Brauch, H., Decker, J., Niehans, G., Hughson, M.D., Moch, H., Storkel, S., Lerman, M.I., Linehan, W.M. and Zbar, B. 1997. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nature Genetics 16, 68-73. [PMID: 9140397]
6. Tambini, C.E., George, A.M., Rommens, J.M., Tsui, L.-C., Scherer, S.W. and Thacker, J. 1997. The XRCC2 DNA repair gene: identification of a positional candidate. Genomics 41, 84-92. [PMID: 9126486]
7. Crackower, M.A., Scherer, S.W., Heng, H.H.Q. and Tsui, L.-C. 1997. Cloning of a DSS1 pseudogene (DSS1P1) and mapping to human chromosome band 5q14. Mammalian Genome 8, 159-160. [PMID: 9060422]
8. Roessler, E., Ward, D.E., Gaudenz, K., Belloni, E., Scherer, S.W., Donnai, D., Siegel-Bartelt, J., Tsui, L.-C. and Muenke, M. 1997. Cytogenetic rearrangements involving the loss of the Sonic hedgehog gene at 7q36 cause holoprosencephaly. Human Genetics 100, 172-181. [PMID: 9254845]
9. Krebs, I., Weis, I., Hudler, M., Rommens, J.M., Roth, H., Scherer, S.W., Tsui, L.-C., Füchtbauer, E-M., Grzeschik, K-H., Tsuji, K. and Kunz, J. 1997. Translocation breakpoint maps 5 kb 3' from TWIST in a patient affected with Saethre-Chotzen syndrome. Human Molecular Genetics 6, 1079-1086. [PMID: 9215678]
10. Edelson, M.I., Scherer, S.W., Tsui, L.-C., Welch, W.R., Bell, D.A., Berkowitz, R.S. and Mok, S.C. 1997. Identification of a 1300 kilobase deletion unit on chromosome 7q31.3 in invasive epithelial ovarian carcinomas. Oncogene 14, 2979-2984. [PMID: 9205105]
11. Nasir, J., Theilmann, J.L., Vaillancourt, J.P., Munday, N.A., Ali, A., Scherer, S., Beatty, B., Nicholson, D.W. and Hayden, M.R. 1997. Interleukin-1beta-converting enzyme (ICE) and related cell death genes ICErel-II and ICErel-III map to the same PAC clone at band 11q22.2-22.3. Mammalian Genome 8, 611-613. [PMID: 8250871]
12. Osborne, L.R., Soder, S., Shi, X.-M., Pober, B., Costa, T., *Scherer, S.W. and Tsui, L.-C. 1997. Hemizygous deletion of syntaxin 1A gene in individuals with Williams syndrome. American Journal of Human Genetics 61, 449-452. *corresponding author [PMID: 9311751]
13. Roessler, E., Belloni, E., Gaudenz, K., Vargas, F., Scherer, S.W., Tsui, L.-C. and Muenke, M. 1997. Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly. Human Molecular Genetics 6, 1847-1853. [PMID: 9302262]
14. Crackower, M.A., Heng, H.H.Q., Shi, X.-M., Scherer, S.W. and Tsui, L.-C. 1997. Fluorescent in situ mapping of the murine deleted in split hand/split foot 1 (dss1) gene to chromosome 6. Mammalian Genome 8, 704. [PMID: 9271682]
15. Hegele, R.A., Connelly, P.W., Scherer, S.W., Hanley, A.J.G., Harris, S.B., Tsui, L.-C. and Zinman, B. 1997. Paraoxanase-2 gene (PON2) G148 variant associated with elevated fasting plasma glucose in noninsulin-dependent diabetes mellitus. Journal of Clinical Endocrinology and Metabolism 82, 3373-3377. [PMID: 9329371]
16. Duh, F.M., Scherer, S.W., Tsui, L.-C., Lerman, M., Zbar, B. and Schmidt, L. 1997. Gene structure of the human MET proto-oncogene. Oncogene 15, 1583-1586. [PMID: 9380410]
17. Scherer, S.W., Soder, S., Duvoisin, R.M., Huizenga, J.J. and Tsui, L.-C. 1997. The human metabotropic glutamate receptor 8 (GRM8) gene: a disproportionately large gene located at 7q31.3-q32.1. Genomics 44, 232-236. [PMID: 9299241]
18. Odermatt, A., Taschner, P.E.M., Scherer, S.W., Beatty, B., Khanna, V.K. Cornblath, D.R., Chaudry, V., Yee, W.-C., Schrank, B., Karpati, G., Breuning, M.H., Knoers, N. and MacLennan, D.H. 1997. Characterization of the gene encoding human sarcolipin (SLN), a proteolipid associated with SERCA1: absence of structural mutations in five patients with Brody disease. Genomics 45, 541-553. [PMID: 9367679]
19. Osborne, L.R., Herbrick, J.-A., Greavette, T., Heng, H.H.Q., Tsui, L.-C. and Scherer, S.W. 1997. PMS-2-related genes flank the rearrangement breakpoints associated with Williams syndrome and other diseases on human chromosome 7. Genomics 45, 402-406. [PMID: 9344666]
20. Freund, C.L., Gregory-Evans, C.Y., Furukawa, T., Papaioannou, M., Looser, J., Ploder, L., Bellingham, J., Ng, D., Herbrick, J.S., Duncan, A., Scherer, S.W., Tsui, L.-C., Loutradis-Anagnostou, A., Jacobson, S.G., Cepko, C., Bhattacharya, S.S. and McInnes, R. 1997. Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor. Cell 91, 543-553. [PMID: 9390563] [12780]
21. Hegele, R., Connelly, P.W., Scherer, S.W., Hanley, A.J.G., Harris, S.B., Tsui, L.-C. and Zinman, B. 1997. Paraoxonase-2 gene G148 variant in an aboriginal Canadian girl with non-insulin dependent diabetes. Lancet 350, 785. [PMID: 9298006] [GO12317]
22. Mueller, H.-W., Michel, A., Heckel, D., Fischer, U., Tönnes, M., Tsui, L.-C., Scherer, S.W., Zang, K.D. and Meese, E. 1997. Identification of an amplified gene cluster in glioma including two novel amplified genes isolated by exon trapping. Human Genetics 101, 109-197. [PMID: 9402967]