Web sites:
The Centre for Applied Genomics
The Chromosome 7 Project
Database of Genomic Variants

News:
Press Releases and Articles
Lay Reviews/Opinions/Editorials
Media/Scientific News Articles
Interviews
Dr. Scherer's Innovation Profile - TRRA - IGLOO

Contact Info:
Stephen W. Scherer
The Centre for Applied Genomics
The Hospital for Sick Children
14th Floor, Toronto Medical Discovery Tower/MaRS Discovery District
101 College St., Toronto, Ontario, M5G 1L7, Canada
(416) 813-7613 (office)
(416) 813-8319 (fax)

Jenny Kaderali,
Dr. Scherer's Assistant
Phone: (416) 813-7654 x1574     Fax: (416) 813-8319

43. Jerome, C.A., Scherer, S.W., Tsui, L.-C., Gietz, R.D. and Triggs-Raine, B. 1997. Assignment of growth factor receptor-bound protein 10 (GRB10) to human chromosome 7p11.2-p12. Genomics 40, 215-216. [PMID: 9070953]
44. Fischer, K., Fröhling, S., Scherer, S.W., McAllister Brown, J., Scholl, C., Stilgenbauer, S., Tsui, L.-C., Lichter, P. and Döhner, H. 1997. Molecular cytogenetic delineation of deletions and translocations involving chromosome band 7q22 in myeloid leukemias. Blood 89, 2036-2041. [PMID: 9058725]
45. Alley, T.L., Scherer, S.W., Huizenga, J.J., Tsui, L.-C. and Wallace, M.R. 1997. Physical mapping of the chromosome 7 breakpoint region in an SLOS patient with t(7;20)(q32.1;q13.2). American Journal of Medical Genetics 68, 279-281. [PMID: 9024559]
46. Zeng, W.R., Scherer, S.W., Koutsilieris, M., Huizenga, J.J., Filteau, F., Tsui, L.-C. and Nepveu, A. 1997. Loss of heterozygosity and reduced expression of the CUTL1 gene in uterine leiomyomas. Oncogene 14, 2355-2365. [PMID: 9178912]
47. Schmidt, L., Duh, F.-M., Chen, F., Kishida, T., Glenn, G., Choyke, P., Scherer, S.W., Zhuang, Z., Lubensky, I., Dean, M., Allikmets, R., Chidambaram, A., Bergerheim, U.R., Feltis, J.T., Casadevall, C., Zamarron, A., Bernues, M., Richard, S., Lips, C.J.M., Walther, M.M., Tsui, L.-C., Geil, L., Orcutt, M.L., Stackhouse, T., Lipan, J., Slife, L., Brauch, H., Decker, J., Niehans, G., Hughson, M.D., Moch, H., Storkel, S., Lerman, M.I., Linehan, W.M. and Zbar, B. 1997. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nature Genetics 16, 68-73. [PMID: 9140397]
48. Tambini, C.E., George, A.M., Rommens, J.M., Tsui, L.-C., Scherer, S.W. and Thacker, J. 1997. The XRCC2 DNA repair gene: identification of a positional candidate. Genomics 41, 84-92. [PMID: 9126486]
49. Crackower, M.A., Scherer, S.W., Heng, H.H.Q. and Tsui, L.-C. 1997. Cloning of a DSS1 pseudogene (DSS1P1) and mapping to human chromosome band 5q14. Mammalian Genome 8, 159-160. [PMID: 9060422]
50. Roessler, E., Ward, D.E., Gaudenz, K., Belloni, E., Scherer, S.W., Donnai, D., Siegel-Bartelt, J., Tsui, L.-C. and Muenke, M. 1997. Cytogenetic rearrangements involving the loss of the Sonic hedgehog gene at 7q36 cause holoprosencephaly. Human Genetics 100, 172-181. [PMID: 9254845]
51. Krebs, I., Weis, I., Hudler, M., Rommens, J.M., Roth, H., Scherer, S.W., Tsui, L.-C., Füchtbauer, E-M., Grzeschik, K-H., Tsuji, K. and Kunz, J. 1997. Translocation breakpoint maps 5 kb 3' from TWIST in a patient affected with Saethre-Chotzen syndrome. Human Molecular Genetics 6, 1079-1086. [PMID: 9215678]
52. Edelson, M.I., Scherer, S.W., Tsui, L.-C., Welch, W.R., Bell, D.A., Berkowitz, R.S. and Mok, S.C. 1997. Identification of a 1300 kilobase deletion unit on chromosome 7q31.3 in invasive epithelial ovarian carcinomas. Oncogene 14, 2979-2984. [PMID: 9205105]
53. Nasir, J., Theilmann, J.L., Vaillancourt, J.P., Munday, N.A., Ali, A., Scherer, S., Beatty, B., Nicholson, D.W. and Hayden, M.R. 1997. Interleukin-1beta-converting enzyme (ICE) and related cell death genes ICErel-II and ICErel-III map to the same PAC clone at band 11q22.2-22.3. Mammalian Genome 8, 611-613. [PMID: 8250871]
54. Osborne, L.R., Soder, S., Shi, X.-M., Pober, B., Costa, T., *Scherer, S.W. and Tsui, L.-C. 1997. Hemizygous deletion of syntaxin 1A gene in individuals with Williams syndrome. American Journal of Human Genetics 61, 449-452. *corresponding author [PMID: 9311751]
55. Roessler, E., Belloni, E., Gaudenz, K., Vargas, F., Scherer, S.W., Tsui, L.-C. and Muenke, M. 1997. Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly. Human Molecular Genetics 6, 1847-1853. [PMID: 9302262]
56. Crackower, M.A., Heng, H.H.Q., Shi, X.-M., Scherer, S.W. and Tsui, L.-C. 1997. Fluorescent in situ mapping of the murine deleted in split hand/split foot 1 (dss1) gene to chromosome 6. Mammalian Genome 8, 704. [PMID: 9271682]
57. Hegele, R.A., Connelly, P.W., Scherer, S.W., Hanley, A.J.G., Harris, S.B., Tsui, L.-C. and Zinman, B. 1997. Paraoxanase-2 gene (PON2) G148 variant associated with elevated fasting plasma glucose in noninsulin-dependent diabetes mellitus. Journal of Clinical Endocrinology and Metabolism 82, 3373-3377. [PMID: 9329371]
58. Duh, F.M., Scherer, S.W., Tsui, L.-C., Lerman, M., Zbar, B. and Schmidt, L. 1997. Gene structure of the human MET proto-oncogene. Oncogene 15, 1583-1586. [PMID: 9380410]
59. Scherer, S.W., Soder, S., Duvoisin, R.M., Huizenga, J.J. and Tsui, L.-C. 1997. The human metabotropic glutamate receptor 8 (GRM8) gene: a disproportionately large gene located at 7q31.3-q32.1. Genomics 44, 232-236. [PMID: 9299241]
60. Odermatt, A., Taschner, P.E.M., Scherer, S.W., Beatty, B., Khanna, V.K. Cornblath, D.R., Chaudry, V., Yee, W.-C., Schrank, B., Karpati, G., Breuning, M.H., Knoers, N. and MacLennan, D.H. 1997. Characterization of the gene encoding human sarcolipin (SLN), a proteolipid associated with SERCA1: absence of structural mutations in five patients with Brody disease. Genomics 45, 541-553. [PMID: 9367679]
61. Osborne, L.R., Herbrick, J.-A., Greavette, T., Heng, H.H.Q., Tsui, L.-C. and Scherer, S.W. 1997. PMS-2-related genes flank the rearrangement breakpoints associated with Williams syndrome and other diseases on human chromosome 7. Genomics 45, 402-406. [PMID: 9344666]
62. Freund, C.L., Gregory-Evans, C.Y., Furukawa, T., Papaioannou, M., Looser, J., Ploder, L., Bellingham, J., Ng, D., Herbrick, J.S., Duncan, A., Scherer, S.W., Tsui, L.-C., Loutradis-Anagnostou, A., Jacobson, S.G., Cepko, C., Bhattacharya, S.S. and McInnes, R. 1997. Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor. Cell 91, 543-553. [PMID: 9390563] [12780]
63. Hegele, R., Connelly, P.W., Scherer, S.W., Hanley, A.J.G., Harris, S.B., Tsui, L.-C. and Zinman, B. 1997. Paraoxonase-2 gene G148 variant in an aboriginal Canadian girl with non-insulin dependent diabetes. Lancet 350, 785. [PMID: 9298006] [GO12317]
64. Mueller, H.-W., Michel, A., Heckel, D., Fischer, U., Tönnes, M., Tsui, L.-C., Scherer, S.W., Zang, K.D. and Meese, E. 1997. Identification of an amplified gene cluster in glioma including two novel amplified genes isolated by exon trapping. Human Genetics 101, 109-197. [PMID: 9402967]