Websites:
The Centre for Applied Genomics
The Chromosome 7 Project
Database of Genomic Variants
McLaughlin Centre
Steve Scherer's Wiki

News:
Press Releases and Articles
Lay Reviews/Opinions/Editorials
Media/Scientific News Articles
Interviews
Video presentation and interview
Integrative research at TCAG [Video]

Contact Info:
Stephen W. Scherer
The Centre for Applied Genomics
The Hospital for Sick Children
Peter Gilgan Centre for Research and Learning
686 Bay Street, Room 13.9800
Toronto, Ontario, M5G 0A4, Canada
(416) 813-7613 (office)
(416) 813-8319 (fax)

Elaine Chang
Dr. Scherer's Assistant
Phone: (416) 813-7654 x301574
Fax: (416) 813-8319

1. Scherer, S.W., Duvoisin, R.M., Kuhn, R., Heng, H.H.Q., Belloni, E. and Tsui, L.-C. 1996. Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q. Genomics 31, 230-233. [PMID: 8824806]
2. Schanen, N.C., Scherer, S.W., Tsui, L.-C. and Francke, U. 1996. Assignment of the 5-hydroxytryptamine (serotonin) receptor 5A (HTR5A) gene to human chromosome band 7q36.1. Cytogenetics and Cell Genetics 72, 187-188. [PMID: 8978771]
3. Takahara, K., Osborne, L., Elliot, R.W., Tsui, L.-C., Scherer, S.W., and Greenspan, D.S. 1996. Fine mapping of the human and mouse genes for the type I procollagen COOH-terminal proteinase enhancer protein. Genomics 31, 253-256. [PMID: 8824813]
4. Tosi, S., Harbott, J., Haas, O.A., Douglas, A., Hughes, D.M., Ross, F., Biondi, A., Scherer, S.W. and Kearney, L. 1996. Classification of deletions and identification of cryptic translocations involving 7q by fluorescence in situ hybridization (FISH). Leukemia 10, 644-649. [PMID: 8618441]
5. Hoglund, P., Haila, S., Scherer, S.W., Tsui, L.C., Green, E.D., Weissenbach, J., Holmberg, C., de la Chapelle, A. and Kere, J. 1996. Positional candidate genes for congenital chloride diarrhea suggested by high-resolution physical mapping in chromosome 7q31. Genome Research 6, 202-210. [PMID: 8963897]
6. Crackower, M.A.*, Scherer, S.W.*, Rommens, J.M., Hui, C.C., Poorkaj, P., Soder, S., Cobben, J.M., Hudgins, L., Evans, J.P. and Tsui, L.-C. 1996. Characterization of the split hand/split foot malformation locus SHFM1 at 7q21.3-q22.1 and analysis of a candidate gene for its expression during limb development. Human Molecular Genetics 5, 571-579. *contributed equally to the manuscript. [PMID: 8733122]
7. Ignatius, J., Knuutila, S., Scherer, S.W., Trask, B. and Kere, J. 1996. Split hand/split foot malformation, deafness, and mental retardation with a complex cytogenetic rearrangement involving 7q21.3. Journal of Medical Genetics 33, 507-510. [PMID: 8782053]
8. Johnson, E.J., Scherer, S.W., Osborne, L., Tsui, L.-C., Oscier, D., Mould, S. and Cotter, F. 1996. Molecular definition of a narrow interval at 7q22.1 associated with myelodysplasia. Blood 87, 3579-3586. [PMID: 8611680]
9. Scherer, S.W., Feinstein, D., Oliveira, L., Tsui, L.-C. and Pittler, S.J. 1996. Gene structure and chromosome localization to 7q21.3 of the human rod photoreceptor transducin gamma-subunit gene (GNGT1). Genomics 35, 241-243. [PMID: 8661128]
10. Lin, J.C., Scherer, S.W., Tougas, L., Traverso, G., Tsui, L.-C., Andrulis, I., Jothy, S. and Park, M. 1996. Detailed deletion mapping with a refined physical map of 7q31 localizes a putative tumor suppressor gene for breast cancer in the region of MET. Oncogene 13, 2001-2008. [PMID: 8934547]
11. Molnar, A., Wu, P., Largespada, D., Vortkamp, A., Scherer, S.W., Copeland, N.G., Jenkins, N.A., Bruns, G. and Georgeopoulos, K. 1996. The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse. Journal of Immunology 156, 585-592. [PMID: 8543809]
12. Rowles, J.C., Scherer, S.W., Xi, T., Majer, M., Nickle, D.C., Rommens, J., Popov, K., Harris, R.A., Riebow, N.L., Xia, J., Tsui, L.-C., Bogardus, C. and Prochazka, M. 1996. Cloning and characterization of PDK4 on 7q21.3 encoding a fourth pyruvate dehydrogenase kinase isoenzyme in human. Journal of Biological Chemistry 271, 22376-22382. [PMID: 8798399]
13. Osborne, L.R., Martindale, D., Scherer, S.W., Shi, X.-M., Huizenga, J., Heng, H.H.Q., Costa, T., Pober, B., Lew, L., Brinkman, J., Rommens, J.M., Koop, B. and Tsui, L.-C. 1996. Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome. Genomics 36, 328-336. [PMID: 8812460]
14. Rozman, D., Stromsted, M., Tsui, L.-C., Scherer, S.W. and Waterman, M.R. 1996. Structure and mapping of the human lanosterol 14alpha-demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; comparison of exon/intron organization with other mammalian and fungal CYP genes. Genomics 38, 371-381. [PMID: 8975714]
15. Eppert, K., Scherer, S.W., Ozcelik, H., Pirone, R., Hoodless, P., Kim, H., Tsui, L.-C., Bapat, B., Gallinger, S., Andrulis, I.L., Thomsen, G.H., Wrana, J.L. and Attisano, L. 1996. MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 86, 543-552. [PMID: 8752209]
16. Mackay, M., Fantes, J., Scherer, S.W., Boyle, S., West, K., Tsui, L.-C., Belloni, E., Lutz, E., Van Heyningen, V. and Harmar, A.J. 1996. Chromosomal localization in mouse and human of the vasoactive intestinal peptide receptor type 2 gene: a possible contributor to the holoprosencephaly 3 phenotype. Genomics 37, 345-353. [PMID: 8938447]
17. Belloni, E., Muenke, M., Roessler, E., Traverso, G., Siegel-Bartelt, J., Frumkin, A., Mitchell, H.F., Donis-Keller, H., Helms, C., Hing, A.V., Heng, H.H.Q., Koop, B., Martindale, D., Rommens, J.M., Tsui, L.-C. and Scherer, S.W. 1996. Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly. Nature Genetics 14, 353-356. [PMID: 8896571]
18. Roessler, E., Belloni, E., Gaudenz, K., Jay, P., Berta, P., Scherer, S.W., Tsui, L.-C. and Muenke, M. 1996. Mutations in the human Sonic Hedgehog gene cause holoprosencephaly. Nature Genetics 14, 357-360. [PMID: 8896572]
19. Gaedigk, R., Karges, W., Hui, M.F., Scherer, S.W. and Dosch, H-M. 1996. Genomic organization and transcript analysis of ICAp69, a target antigen in diabetic autoimmunity. Genomics 38, 382-391. [PMID: 8975715]
20. Nakabayashi, K., Ogata, T., Fujii, M., Takahashi, E., Ogino, H., Michishita, E., Scherer, S.W., Tsui, L.-C. and Ayusawa, D. 1996. A panel of radiation hybrids defining the 7q31-q32 region of human chromosome 7. DNA Research 3, 181-183. [PMID: 8905237]