Websites:
The Centre for Applied Genomics
The Chromosome 7 Project
Database of Genomic Variants
McLaughlin Centre
Steve Scherer's Wiki

News:
Press Releases and Articles
Lay Reviews/Opinions/Editorials
Media/Scientific News Articles
Interviews
Video presentation and interview
Integrative research at TCAG [Video]

Contact Info:
Stephen W. Scherer
The Centre for Applied Genomics
The Hospital for Sick Children
Peter Gilgan Centre for Research and Learning
686 Bay Street, Room 13.9800
Toronto, Ontario, M5G 0A4, Canada
(416) 813-7613 (office)
(416) 813-8319 (fax)

Elaine Chang
Dr. Scherer's Assistant
Phone: (416) 813-7654 x301574
Fax: (416) 813-8319

1. Ling, M., McEachern, G., Seyda, A., MacKay, N., Scherer, S.W., Bratinova, S., Beatty, B., Giovannucci-Uzielli, M.L. and Robinson, B.H. 1998. Detection of a homozygous four base pair deletion in the protein X gene in a case of pyruvate dehydrogenase complex deficiency. Human Molecular Genetics 7, 501-505. [PMID: 9467010]
2. Malik, N., Canfield, V., Sanchez-Watts, G., Watts, A.G., Scherer, S.W., Beatty, B.G., Gros, P. and Levenson, R. 1998. Structural organization and chromosomal localization of the human Na,K-ATPase beta 3 subunit gene and pseudogene. Mammalian Genome 9, 136-143. [PMID: 9457675]
3. White, J.A., Beckett, B., Scherer, S.W., Herbrick, J.-A. and Petkovich, M. 1998. P450RA1 (CYP26A1) maps to human chromosome 10q23-q24 and mouse chromosome19C2-3. Genomics 48, 270-272. [PMID: 9521883]
4. Kusaba, H., Nakayama, M., Harada, T., Torigoe, K., Green, E.D., Scherer, S.W., Kohno, K., Kuwano, M. and Wada, M. 1997. Maintenance of hypomethylation status and preferential expression of exogenous human MDRI/PGY1 gene in mouse L cells by YAC mediated transfer. Somatic Cell and Molecular Genetics 23, 259-274. [PMID: 9542528]
5. Torigoe, K., Harada, T., Kusaba, H., Uchiumi, T., Kohno, K., Green, E.D., Scherer, S.W.,Tsui, L.-C., Schlessinger, D., Kuwano, M. and Wada, M. 1998. Localization of 67 exons on a YAC contig spanning 1.5 Mb around the multidrug resistance gene region of human chromosome 7q21.1. Genomics 49, 14-22. [PMID: 9570944]
6. Csoka, T.B., Frost, G.I., Heng, H.H., Scherer, S.W., Mohapatra, G. and Stern, R. 1998. The hyaluronidase gene HYAL1 maps to chromosome 3p21.2-p21.3 in human and 9F1-F2 in mouse, a conserved candidate tumor suppressor locus. Genomics 48, 63-70. [PMID: 9503017]
7. Leclerc, D., Wilson, A., Dumas, R., Gafuik, C., Song, D., Watkins, D., Heng, H.H.Q., Rommens, J.M., Scherer, S.W., Rosenblatt, D.S. and Gravel, R.A. 1998. Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria. Proc. Natl. Acad. Sci. U.S.A. 95, 3059-3064. [PMID: 9501215]
8. Vargas, F.R., Roessler, E., Gaudenz, K., Belloni, E., Whitehead, A.S., Kirke, P.N., Mills, J.L., Hooper, G., Stevenson, R.E., Cordeiro, I., Correia, P., Felix, T., Gereige, R., Cunningham, M.L., Canun, S., Antonarakis, S.E., Strachan, T., Tsui, L.-C., Scherer, S.W. and Muenke, M. 1998. Analysis of the human Sonic Hedgehog coding and promoter regions in sacral agenesis, triphalangeal thumb, and mirror polydactyly. Human Genetics 102, 387-392. [PMID: 9600232]
9. Coyle, B., Reardon, W., Herbrick, J., Tsui, L.-C., Gausden, E., Lee, J., Coffey, R., Grueters, A., Grossman, A., Phelps, P.D., Luxon, L., Kendall-Taylor, P., Scherer, S.W. and Trembath, R.C. 1998. Molecular analysis of the PDS gene in Pendred syndrome. Human Molecular Genetics 7, 1105-1112. [PMID: 9618167]
10. Mochizuki, H., Scherer, S.W., Xi, T., Nickle, D.C., Majer, M., Huizenga, J.J., Tsui, L-C. and Prochazka, M. 1998. Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence. Gene 213, 149-157. [PMID: 9714608]
11. Mishmar, D., Rahat, A., Scherer, S.W., Nyakatura, G., Hinzmann, B., Kohwi, Y., Mandel-Gutfroind, Y., Lee, J.R., Drescher, B., Sas, D.E., Margalit, H., Platzer, M., Wiess, A., Tsui, L.-C., Rosenthal, A. and Kerem, B. 1998. Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by cloning of a simian virus 40 integration site. Proc. Natl. Acad. Sci. U.S.A. 95, 8141-8146. [PMID: 9653154]
12. Haila, S., Hoglund, P., Scherer, S.W., Lee, J.R., Kristo, P., Coyle, B., Trembath, R., Holmberg, C., de la Chapelle, A. and Kere, J. 1998. Genomic structure of the human congenital chloride diarrhea (CLD) gene. Gene 214, 87-93. [PMID: 9729124]
13. Luo, L., Herbrick, J-A., Scherer, S.W., Beatty, B., Squire, J. and Diamandis, E.P. 1998. Structural characterization and mapping of the normal epithelial cell-specific 1 gene. Biochem. and Biophysic. Res. Com. 247, 580-586. [PMID: 9647736]
14. Boright, A.P., Connelly, P.W., Brunt, J.H., Scherer, S.W., Tsui, L.-C. and Hegele, R.A. 1998. Genetic variation in paraoxonase-1 and paraoxonase-2 is associated with variation in plasma lipoproteins in Alberta Hutterites. Atherosclerosis 139, 131-136. [PMID: 9699900]
15. Jadayel, D.M., Osborne, L.R., Coignet, L.J.A., Zani, V.J., Tsui, L.-C., Scherer, S.W. and Dyer, M.J.S. 1998. The BCL7 gene family: deletion of BCL7B in Williams syndrome. Gene 224, 35-44. [PMID: 9931421]
16. Ross, A.J., Ruiz-Perez, V., Wang, Y., Hagan, D-M., Scherer, S.W., Lynch, S.A., Lindsay, S., Custard, E., Belloni, E., Wilson, D.I., Wadey, R., Goodman, F., Orstavik, K.H., Monclair, T., Robson, S., Reardon, W., Burn, J., Scambler, P. and Strachan, T. 1998. A homeobox gene, HLXB9, is the major locus for dominantly inherited sacral agenesis. Nature Genetics 20, 358-361. [PMID: 9843207]
17. Minassian, B., Lee, J., Herbrick, J., Huizenga, J., Soder, S., Mungall, A, Dunham, I., Gardner, R., Fong, C.Y., Carpenter, S., Jardim, L., Satischandra, P., Andermann, E., Snead, O.C., Lopes-Cendes, I., Tsui, L.-C., Delgado-Escueta, A.V., Rouleau, G.A. and Scherer, S.W. 1998. Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy. Nature Genetics 20, 171-174. [PMID: 9771710]
18. Dohner, K., Brown, J., Hehmann, U., Hetzel, C., Stewart, J., Lowther, G., Scholl, C., Frohling, S., Cuneo, A., Tsui, L.-C., Lichter, P., Scherer, S.W. and Dohner, H. 1998. Molecular cytogenetic characterization of a critical region in bands 7q35-q36 commonly deleted in malignant myeloid disorders. Blood 92, 4031-4035. [PMID: 9834205]
19. Egan, S., Herbrick, J., Tsui, L.-C., Cohen, B., Flock, G., Beatty, B. and Scherer, S.W. 1998. Mapping of the human Lunatic Fringe (LFNG) gene to 7p22 and Manic Fringe (MFNG) to 22q12. Genomics 54, 576-577. [PMID: 9878264]
20. Glockner, G., Scherer, S.W., Schattevoy, R., Boright, A., Weber, J., Tsui, L.-C. and Rosenthal, A. 1998. Large scale sequencing of two regions in human 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes. Genome Research 8, 1060-1073. [PMID: 9799793]
21. Mansour, S.J., Herbrick, Scherer, S.W. and Melancon, P.R. 1998. Human GBF1 is a ubiquitously expressed gene of the sec7 domain family mapping to 10q24. Genomics 54, 323-327. [PMID: 9828135]
22. Hadano, S., Nichol, K., Brinkman, R.R., Nasir, J., Martindale, D., Koop, B.F., Nicholson, D.W., Scherer, S.W., Ikeda, J-E. and Hayden, M.R. 1998. A yeast artificial chromosome-based physical map of the juvenile amyotrophic lateral sclerosis (ALS2) critical region on human chromosome 2q33-34. Genomics 55, 106-112. [PMID: 9889004]
23. Hegele, R.A., Harris, S.B., Zinman, B., Wang, J., Cao, H., Hanley, A.J., Tsui, L.C., Scherer, S.W. 1998. Variation in the AU(AT)-rich element within the 3'-untranslated region of PPP1R3 is associated with variation in plasma glucose in aboriginal Canadians. Journal of Clinical Endocrinology and Metabolism 83, 3980-3983. [PMID: 9814479]
24. Ogino, H., Nakabayashi, K., Michishita, E., Scherer, S.W., Fujii, M., Suzuki, T., Ayusawa, D. 1998. Clustering of human chromosome fragments on the mouse genome by chromosome-mediated gene transfer. DNA Research 5, 247-250. [PMID: 9802571]
25. Xia, J., Scherer, S.W., Cohen, P.T.W., Majer, M., Xi, T., Norman, R.A., Knowler, W.C., Bogaudus, C. and Prochazka, M. 1998. A common variant in PPP1R3 associated with insulin resistance and type 2 diabetes. Diabetes 47, 1519-1524. [PMID: 9726244]
26. de la Puente, A., Velasco, E., Perez Jurado, L.A., Hernandez-Chico, C., van de Rijke, F.M., Scherer, S.W., Raap, A.K. and Cruces, J. 1998. Analysis of the monomeric alphoid sequences in the pericentromeric region of human chromosome 7. Cytogenetics and Cell Genetics 83, 176-181. [PMID: 10072574]
27. Hegele, R.A., Harris, S.B., Connelly, P.W., Hanley, A.J.G., Tsui, L.-C., Zinman, B. and Scherer, S.W. 1998. Genetic variation in paraoxonase-2 is associated with variation in plasma lipoproteins in Canadian Oji-Cree. Clinical Genetics 54, 394-399. [PMID: 9842991]